CD47 Antibody (C-term)

Synthetic Peptide

CD47 antigen, also known as integrin associated protein (IAP), has a very broad tissue distribution. CD47 is expressed on all hematopoietic cells, including leukocytes, platelets and erythrocytes. It is also expressed on epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. There are approximately 50.000 CD47 molecules per erythrocyte. The glycoprotein is deficient in erythrocytes of the rare Rh null phenotype. CD47 is a heavily N glycosylated cell membrane glycoprotein of apparent molecular weight 47-52 kDa. It may play a role as a signaltransducer in the regulation of cation fluxes across cell membranes and in the chemotactic and adhesive interactions of leukocytes with endothelial cells.

Polyclonal

961

Affinity Purified Rabbit Polyclonal Antibody (Pab)

Western blot analysis of CD47 Antibody (C-term) (Cat. #AP9137b) in T47D cell line lysates (35ug/lane). CD47 (arrow) was detected using the purified Pab.

1:1000

35214

HUMAN

NP_001768.1; NP_942088.1