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TPH2 Antibody (Center)

TPH2 Antibody (Center)

ArtNr	ABC-AP9177C
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, FC, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	TPH2, NTPH, Neuronal tryptophan hydroxylase, Tryptophan 5-hydroxylase 2, Tryptophan 5-monooxygenase 2
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Primary Accession	Q8IWU9
Antigen Type	Synthetic Peptide
Application	FC, IHC-P, WB
Bio Background	This protein is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control.
Bio References	Khatua, A.K., et.al., Virology 400 (1), 68-75 (2010) Koning, F.A., et.al., J. Virol. 83 (18), 9474-9485 (2009)
Clonality	Polyclonal
Clone/Animal Names	RB22900
Gene ID	121278
Gene Name	TPH2
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of TPH2 Antibody (Center) (Cat. #AP9177c) in 293 cell line lysates (35ug/lane). TPH2 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	TPH2 Antibody (Center) (Cat. #AP9177c) IHC analysis in formalin fixed and paraffin embedded mouse brain followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TPH2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Legend image 3	TPH2 Antibody (Center) (Cat. #AP9177c) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 3	FC
Dilution image 3	1:10~50
Other Accession	Q8CGU9; Q8CGV2; Q0EAB8
Predicted	Hs, M, Rat
Isotype	Rabbit Ig
Calculated MW	56057
Antigen Region	168-193
Antigen Source	HUMAN
Target/Specificity	This TPH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-193 amino acids from the Central region of human TPH2.
NCBI Accession	NP_775489.2

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ABC-AP9177C-datasheet.pdf

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Menge: 400 ul

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