Puromycin Dihydrochloride, 100 MG

X1001900-0

Puromycin is a protein inhibitor by inhibiting translation.It is toxic to both procaryotic & eukaryotic cells.Puromycin's main function is used in cell biology as a selective antibiotic agent in cell culture systemsfor selecting mammalian cell lines, which have been transformed by vectors that express puromycin-N-acetyl-transferase (PAC). Puromycin’ slongstanding application as a gene selection antibiotic, has a powerful new role in Genome editing utilizing the CRISPR/Cas9 system 1, 2. http://mbio.asm.org/content/6/4/e00861-15.full.pdf+html *Listed below are a few published articles demonstrating the use of our Puromycin. Inquire for a full list of references. The Aryl Hydrocarbon Receptor Binds to E2F1 and Inhibits E2F1-induced Apoptosis , Jennifer L. Marlowe, Yunxia Fan, et al , Aug 2008; 19: 3263 - 3271. High TCL1 expression and intact T-cell receptor signaling define a hyperproliferative subset of T-cell prolymphocytic leukemia , Marco Herling, Kaushali A. Patel, et al , Sep 2008; 111:328-337 CBP and p300 are cyto plasmic E4 polyubiquitin ligases for p53 , Dingding Shi, Marius S. Pop, et al , Sep 2009; vol. 106 no. 38:16275-16280 * Related Sources 9 tips Influencing successful puromycin gene transfection Puromycin FAQs Puromycin-Antitumor Effect and Activity Puromycin; Somatic Cell Cloning

175-177 °C

752.16 °C