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Omadacycline (hydrochloride) Europäischer Partner

ArtNr HY-14865C-500mg
Hersteller MedChem Express
CAS-Nr. 1196800-39-1
Menge 500 mg
Kategorie
Typ Inhibitors
Specific against other
Purity 99.87
Citations [1]Macone AB, et, al. In vitro and in vivo antibacterial activities of omadacycline, a novel aminomethylcycline. Antimicrob Agents Chemother. 2014;58(2):1127-35.|[2]Durães F, et, al. Omadacycline: A Newly Approved Antibacterial from the Class of Tetracyclines. Pharmaceuticals (Basel). 2019 Apr 21;12(2):63.|[3]Zhanel GG, et, al. Omadacycline: A Novel Oral and Intravenous Aminomethylcycline Antibiotic Agent. Drugs. 2020 Feb;80(3):285-313.|[4]Markham A, et, al. Omadacycline: First Global Approval. Drugs. 2018 Dec;78(18):1931-1937.
J Antimicrob Chemother. 2021 Feb 11;76(3):653-658.
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Antimicrob Agents Chemother. 2019 May 24;63(6). pii: e00470-19.
Antimicrob Agents Chemother. 2020 Feb 21;64(3):e02097-19.
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Research Square Preprint. 2020 Jun.
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Smiles O=C(C1=C(O)[C@@H](N(C)C)[C@@](C[C@@]2([H])C(C(C3=C(O)C(CNCC(C)(C)C)=CC(N(C)C)=C3C2)=O)=C4O)([H])[C@@]4(O)C1=O)N.Cl
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Alias PTK0796 hydrochloride,Amadacycline hydrochloride
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Reference compound1
Manufacturer - Applications
COVID-19-immunoregulation
Manufacturer - Category
Reference compound / Active compounds; API
Manufacturer - HS Code
H302, H315, H319, H335
Shipping Temperature
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Product Description
Omadacycline (PTK 0796) hydrochloride, a first-in-class orally active aminomethylcycline antibacterial, is a member of the tetracycline class of antibiotics. Omadacycline hydrochloride acts through the inhibition of bacterial protein synthesis by binding to the 30S ribosomal subunit. Omadacycline hydrochloride possesses broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline hydrochloride can be used for the research of acute bacterial skin and skin-structure infections, community-acquired pneumonia, and urinary tract infections[1][2][3][4].
Manufacturer - Research Area
Infection
Solubility
DMSO : 50 mg/mL (ultrasonic)|H2O : 200 mg/mL (ultrasonic)
Manufacturer - Pathway
Anti-infection
Clinical information
Launched
Isoform
Tetracycline
UNSPSC Code
12352005
Precautionary
H302, H315, H319, H335

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 mg
Lieferbar: In stock
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