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Tigecycline (hydrochloride)

Tigecycline (hydrochloride)

ArtNr	HY-B0117A-5mg
Hersteller	MedChem Express
CAS-Nr.	197654-04-9
Menge	5 mg
Kategorie	Oncology Neuroscience Neural Lineage Markers By Cell Type Blastoma Carcinoma Cell Biology Cell Status Proliferation Inhibitors & Compound Libraries Small Molecules By Organ Bladder Cancer
Typ	Inhibitors
Specific against	other
Purity	99.56
Citations	[1]Jitkova Y, et al. A novel formulation of tigecycline has enhanced stability and sustained antibacterial and antileukemic activity. PLoS One. 2014 May 28;9(5):e95281.\|[2]Falagas ME, et al. Activity of TP-6076 against carbapenem-resistant Acinetobacter baumannii isolates collected from inpatients in Greek hospitals. Int J Antimicrob Agents. 2018 Aug;52(2):269-271. Ann Lab Med. 2021 May 1;41(3):293-301. Emerg Microbes Infect. 2024 Dec;13(1):2321981. Adv Ther (Weinh). 2024 Jan 12. Anim Dis. 2021;1(1):26. Ann Clin Microbiol Antimicrob. 2024 Aug 20;23(1):73. Antimicrob Agents Chemother. 2019 May 24;63(6). pii: e00470-19. Antimicrob Agents Chemother. 2023 Feb 16;67(2):e0145922. Antimicrob Agents Chemother. 2024 Mar 6;68(3):e0112023. Antimicrob Agents Chemother. 2024 Oct 29:e0094524. Antimicrob Agents Chemother. 2025 May 23:e0024925. Authorea. 2025 Sep 17. Biomed Pharmacother. 2023 Dec 31:169:115856. Cell Rep. 2025 Nov 25;44(11):116496. Cell. 2025 May 15;188(10):2757-2777.e22. Clin Exp Pharmacol Physiol. 2023 Jul;50(7):604-609. Cureus. 2024 Dec 1;16(12):e74917. EBioMedicine. 2022 Apr;78:103943. Infect Drug Resist. 2020 Jul 28;13:2617-2629. Infect Drug Resist. 2021 Jun 30;14:2499-2507. Infect Drug Resist. 2023 Apr 17:16:2271-2279. Infect Drug Resist. 2025 Oct 4:18:5239-5247. Infect Genet Evol. 2025 Sep:133:105780. Int J Antimicrob Agents. 2018 Aug;52(2):269-271. Int J Antimicrob Agents. 2025 Jun 9:107551. J Antibiot (Tokyo). 2022 Aug;75(8):463-471. J Antimicrob Chemother. 2025 Apr 10:dkaf105. J Appl Microbiol. 2025 Apr 17:lxaf093. Microb Pathog. 2020 Dec;149:104502. Microbiol Spectr. 2023 Feb 14;11(1):e0323822. Microbiol Spectr. 2023 Jun 15;11(3):e0071823. Microbiol Spectr. 2025 Mar 19:e0134424. Microorganisms. 2024 Mar 13;12(3):575. Nat Commun. 2022 Mar 2;13(1):1116. Nat Commun. 2024 Jun 28;15(1):5481. Naunyn Schmiedebergs Arch Pharmacol. 2025 Oct 29. SLAS Discov. 2020 Sep;25(8):895-905. Vet Microbiol. 2024 May:292:110046. World J Microbiol Biotechnol. 2024 Jun 6;40(8):233.
Smiles	O=C(C(C1=O)=C(O)[C@@H](N(C)C)[C@]2([H])C[C@]3([H])CC4=C(C(C3=C(O)[C@@]21O)=O)C(O)=C(NC(CNC(C)(C)C)=O)C=C4N(C)C)N.Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	GAR-936 hydrochloride
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Reference compound1
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Category	Reference compound / Active compounds; API
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Product Description	Tigecycline hydrochloride (GAR-936 hydrochloride) is a broad-spectrum glycylcycline antibiotic. The mean inhibitory concentration (MIC) of Tigecycline for E. coli (MG1655 strain) is approximately 125 ng/mL[1]. MIC50 and MIC90 are 1 and 2 mg/L for Acinetobacter baumannii (A. baumannii), respectively[2].
Manufacturer - Research Area	Cancer; Infection
Solubility	10 mM in DMSO
Manufacturer - Pathway	Anti-infection; Autophagy
Clinical information	Launched
UNSPSC Code	12352005

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