Azelastine

ArtNr	HY-B0462A-5mg
Hersteller	MedChem Express
CAS-Nr.	58581-89-8
Menge	5 mg
Kategorie	Food Safety Histamines Metabolism Diabetes Glucose Homeostasis Cell Biology Cell Stainings ECM Inhibitors & Compound Libraries Small Molecules
Typ	Inhibitors
Specific against	other
Purity	999.200
Citations	[1]Craig La Force. Review of the pharmacology, clinical efficacy, and safety of azelastine hydrochloridel. Expert Rev Clin Immunol. 2005 Jul;1(2):191-201.\|[2]Mohamed M Elseweidy, et al. Azelastine a potent antihistamine agent, as hypolipidemic and modulator for aortic calcification in diabetic hyperlipidemic rats model. Arch Physiol Biochem. 2020 Jul 2;1-8.\|[3]Carlos D. Zappia, et al. Azelastine potentiates antiasthmatic dexamethasone effect on a murine asthma model. Pharmacol Res Perspect. 2019 Dec; 7(6): e00531.\|[4]Li Yang, et al. Identification of SARS-CoV-2 entry inhibitors among already approved drugs. Acta Pharmacol Sin. 2020 Oct 28 : 1-7.\|[5]Shao-Cheng Liu, et al. Effect of budesonide and azelastine on histamine signaling regulation in human nasal epithelial cells. Eur Arch Otorhinolaryngol. 2017 Feb;274(2):845-853. Phytomedicine. 2023 Jul 25:116:154825. bioRxiv. 2025 Sep 4. Pharm Res. 2025 Aug;42(8):1315-1329.
Smiles	O=C1N(C2CCN(C)CCC2)N=C(CC3=CC=C(Cl)C=C3)C4=C1C=CC=C4
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Reference compound1
Manufacturer - Applications	Metabolism-protein/nucleotide metabolism
Manufacturer - Category	Reference compound / Active compounds; API
Manufacturer - HS Code	H302-H315-H319-H335
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Product Description	Azelastine, an antihistamine, is a potent and selective histamine 1 (H1) antagonist. Azelastine can be used for the research of allergic rhinitis, asthma, diabetic hyperlipidemic and SARS-CoV-2[1][2][3][4].
Manufacturer - Research Area	Infection; Endocrinology; Metabolic Disease; Inflammation/Immunology
Solubility	DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	Anti-infection; GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Clinical information	Launched
Isoform	H1 Receptor
UNSPSC Code	12352005
Precautionary	P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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