Histamine

ArtNr	HY-B1204-1g
Hersteller	MedChem Express
CAS-Nr.	51-45-6
Menge	1 g
Kategorie	Food Safety Histamines Inhibitors & Compound Libraries Small Molecules
Typ	Inhibitors
Specific against	other
Purity	99.99
Citations	[1]Okabe S, et al. Effects of cimetidine, a histamine H2-receptor antagonist, on various experimental gastric and duodenal ulcers. Am J Dig Dis. 1977 Aug;22(8):677-84. \|[2]Rietveld S et al. The influence of respiratory sounds on breathlessness in children with asthma: a symptom-perceptionapproach. Health Psychol. 1997 Nov;16(6):547-53. \|[3]Malmberg-Aiello P, et al., Role of histamine in rodent antinociception. Br J Pharmacol. 1994 Apr;111(4):1269-79. \|[4]Medina V, et al., Histamine-mediated signaling processes in human malignant mammary cells. Cancer Biol Ther. 2006 Nov;5(11):1462-71.\|[5]Ferreira R, et al., Histamine modulates microglia function. J Neuroinflammation. 2012 May 8;9:90. \|[6]MARTIN L. The effects of histamine on the vaginal epithelium of the mouse. J Endocrinol. 1962 Jan;23:329-40. \|[7]Yang LP, et al. Spotlight on histamine dihydrochloride in acute myeloid leukaemia. Drugs Aging. 2011 Apr 1;28(4):325-9. Adv Sci (Weinh). 2023 Mar;10(7):e2203869. Biochem Biophys Res Commun. 2025 Apr 1:755:151566. Biol Pharm Bull. 2023;46(6):864-868. bioRxiv. 2024 June 12. Br J Pharmacol. 2021 Apr;178(7):1669-1683. Cancer Cell. 2022 Oct 10;40(10):1111-1127.e9. FASEB J. 2025 Jul 15;39(13):e70778. Fishes. 2025 Aug 14. Front Pharmacol. 2019 Nov 15;10:1380. J Agric Food Chem. 2025 Nov 19;73(46):29604-29618. J Cell Commun Signal. 2023 Mar;17(1):151-165. Microbiol Spectr. 2023 Jan 31;11(2):e0469822. Pharm Res. 2025 Aug;42(8):1315-1329. Immunity. 2025 Aug 12:S1074-7613(25)00314-0. mBio. 2022 Oct 26;13(5):e0200422. Insect Sci. 2025 Sep 11. JID Innov. 2025 Apr 3;5(4):100369.
Smiles	NCCC1=CN=CN1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Ergamine
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Natural Products
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Category	Reference compound / Active compounds; API; Natural Products
Manufacturer - HS Code	H301, H315, H317, H319, H334, H335
Shipping Temperature	Blue Ice
Storage Conditions	-20°C (Powder, stored under nitrogen, away from moisture)
Product Description	Histamine is the agonist for histamine receptor and a vasodilator. Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma[1][2][3][4][5][6][7].
Manufacturer - Research Area	Cancer; Endocrinology; Inflammation/Immunology; Neurological Disease
Solubility	H2O : 125 mg/mL (ultrasonic)
Manufacturer - Pathway	Apoptosis; GPCR/G Protein; Immunology/Inflammation; MAPK/ERK Pathway; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB; PI3K/Akt/mTOR
Clinical information	Launched
Isoform	Human Endogenous Metabolite
UNSPSC Code	12352005
Precautionary	H301, H315, H317, H319, H334, H335

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