Product Description |
BLNK proteins function as central linkers downstream of the B cell receptor (BCR), bridging SYK kinases to various signaling pathways and regulating B cell function and development. It activates ERK/EPHB2, MAP kinase p38 and JNK, regulates AP1 activation, and plays a key role in NF-kappa-B and NFAT activation. BLNK Protein, Human (HEK293, His) is the recombinant human-derived BLNK protein, expressed by HEK293 , with N-His labeled tag. The total length of BLNK Protein, Human (HEK293, His) is 456 a.a., with molecular weight of 95-100 kDa. |