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BAFF and Receptor Detection Set

ArtNr PRS-PSI-1803-1Set
Hersteller ProSci
Menge 1 Set
Kategorie
Typ Detection Sets
Format Liquid
Applikationen WB, IF, IHC
Specific against Human (Homo sapiens)
Citations Moore PA, Belvedere O, Orr A, et al. BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator. >Science 1999; 285:260-3.
Schneider P, MacKay F, Steiner V, et al. BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth. J Exp Med 1999; 189:1747-56.
Shu HB, Hu WH, Johnson H. TALL-1 is a novel member of the TNF family that is down-regulated by mitogens. J Leuk Biol 1999; 65:680-3.
Hahne M, Kataoka T, Schroter M, et al. APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth. J Exp Med. 1998; 188(6):1185-90.
ECLASS 10.1 32161090
ECLASS 11.0 32161090
UNSPSC 41116126
Lieferbar
Storage Conditions
Stable at 4°C for three months, store at -20°C for up to one year.
Background
Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members were recently identified by several groups and designated BAFF and APRIL. Both proteins stimulate B cell proliferation, humoral immune responses, NF-κ B activation, and apoptosis. Two receptors, TACI and BCMA, recognize both BAFF and APRIL; a third receptor, BAFF-R, is specific for BAFF. These ligands and their receptors are involved in the development of autoimmune diseases as well as cancer.

For images please see PDF data sheet
Set Contents
BAFF Antibody, Cat. No. 2221 (50 μg)

APRIL Antibody, Cat. No. 2415 (50 μg)

TACI Antibody, Cat. No. 2395 (50 μg)

BCMA Antibody, Cat. No. 2397 (50 μg)

BAFF-R Antibody, Cat. No. 3097 (50 μg)
Purification
Antibodies are supplied as affinity chromatography purified IgG.
Concentration
Antibody 1 mg/mL
Buffer
PBS containing 0.02% sodium azide.
Immunogen
Rabbit polyclonal antibodies were raised against peptides corresponding to amino acid sequences from each of the corresponding proteins.
Clonality
Polyclonal
Disclaimer
This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 Set
Lieferbar: In stock
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