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FGF2 Mouse Monoclonal Antibody [Clone ID: LBI2H11]

ArtNr LBI-AMM08912V
Hersteller Leading Biology
Menge 100 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid
Clon LBI2H11
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG1
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias BFGF, FGF-2, FGFB, HBGF-2
Lieferbar
Manufacturer - Category
mAbs-V
Manufacturer - Targets
FGF2
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research
MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton
Overview
bFGF (FGF2) mouse monoclonal antibody, clone LBI2H11
Immunogen
Human recombinant protein fragment corresponding to amino acids 10-155 of human bFGF (NP_001997) produced in E.coli.
Gene Name
fibroblast growth factor 2
Symbol
FGF2
Function
Druggable Genome, Secreted Protein
Summary
BFGF is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
Manufacturer - Format
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration
1 mg/ml
Storage Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution
WB 1:5000~10000
Purification
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway
MAPK signaling pathway, Melanoma, Pathways in cancer, Regulation of actin cytoskeleton

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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