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PDX1 Mouse Monoclonal Antibody [Clone ID: LBI5D5]

PDX1 Mouse Monoclonal Antibody [Clone ID: LBI5D5]

ArtNr	LBI-AMM08931VCF
Hersteller	Leading Biology
Menge	100 ug
Kategorie	Metabolism Diabetes Glucose Homeostasis Antibodies
Typ	Antibody Monoclonal
Format	Lyophilized
Clon	LBI5D5
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Konjugat/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	GSF, IDX-1, IPF1, IUF1, MODY4, PAGEN1, PDX-1, STF-1
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Manufacturer - Category	mAbs-V
Manufacturer - Targets	PDX1
Storage Conditions	Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Maturity onset diabetes of the young, Type II diabetes mellitus
Overview	Carrier-free (BSA/glycerol-free) Pdx1 mouse monoclonal antibody, clone LBI5D5
Immunogen	Full length human recombinant protein of human PDX1 (NP_000200) produced in E.coli.
Gene Name	Homo sapiens pancreatic and duodenal homeobox 1 (PDX1), mRNA.
Symbol	PDX1
Function	Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors
Summary	Pdx1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. It is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in PDX1 gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Manufacturer - Format	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Buffer	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Dilution	WB 1:5000~10000
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Maturity onset diabetes of the young, Type II diabetes mellitus

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ug

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Lieferung vsl. bis 15.01.2026

Express-Lieferung: 21 Tage sparen

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