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TrkC (NTRK3) Mouse Monoclonal Antibody [Clone ID: LBI2B8]

TrkC (NTRK3) Mouse Monoclonal Antibody [Clone ID: LBI2B8]

ArtNr	LBI-AMM09205V
Hersteller	Leading Biology
Menge	100 ul
Kategorie	Oncology Neuroscience Molecular Targets for Neuroscience Antibodies By Cell Type Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma
Typ	Antibody Monoclonal
Format	Liquid
Clon	LBI2B8
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Konjugat/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	GP145-TrkC, TRKC, gp145(trkC)
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Manufacturer - Category	mAbs-V
Manufacturer - Targets	NTRK3
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Neurotrophin signaling pathway
Overview	Anti-NTRK3 (TrkC) mouse monoclonal antibody, clone LBI2B8
Immunogen	Full-length protein expressed in 293T cell transfected with human NTRK3 expression vector
Gene Name	neurotrophic receptor tyrosine kinase 3
Symbol	NTRK3
Function	Druggable Genome, Protein Kinase, Transmembrane
Summary	This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.
Manufacturer - Format	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Storage Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution	WB 1:2000, IHC 1:50, IF 1:100
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Neurotrophin signaling pathway

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Menge: 100 ul

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Lieferung vsl. bis 15.01.2026

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