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BTK Mouse Monoclonal Antibody [Clone ID: LBI15G8]

ArtNr LBI-AMM09738VCF
Hersteller Leading Biology
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Format Lyophilized
Clon LBI15G8
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG1
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias AGMX1, AT, ATK, BPK, IMD1, PSCTK1, XLA
Lieferbar
Manufacturer - Category
mAbs-V
Manufacturer - Targets
BTK
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research
B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Primary immunodeficiency
Overview
Carrier-free (BSA/glycerol-free) BTK mouse monoclonal antibody, clone LBI15G8
Immunogen
Full length human recombinant protein of human BTK (NP_000052) produced in HEK293T cell.
Gene Name
Homo sapiens Bruton tyrosine kinase (BTK), transcript variant 1, mRNA.
Symbol
BTK
Function
Druggable Genome, Protein Kinase
Summary
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement.
Manufacturer - Format
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Dilution
WB 1:2000, IHC 1:50, IF 1:100, Flow 1:100
Purification
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway
B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Primary immunodeficiency

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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