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Pyruvate Kinase (PKLR) Mouse Monoclonal Antibody [Clone ID: LBI1F3]

Pyruvate Kinase (PKLR) Mouse Monoclonal Antibody [Clone ID: LBI1F3]

ArtNr	LBI-AMM10007VCF
Hersteller	Leading Biology
Menge	100 ug
Kategorie	Metabolism Glucose Homeostasis Antibodies
Typ	Antibody Monoclonal
Format	Lyophilized
Clon	LBI1F3
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG2a
Konjugat/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	PK1, PKL, PKR, PKRL, RPK
Lieferbar
Manufacturer - Category	mAbs-V
Manufacturer - Targets	PKLR
Storage Conditions	Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Glycolysis / Gluconeogenesis, Insulin signaling pathway, Maturity onset diabetes of the young, Metabolic pathways, Purine metabolism, Pyruvate metabolism, Type II diabetes mellitus
Overview	Carrier-free (BSA/glycerol-free) PKLR mouse monoclonal antibody, clone LBI1F3
Immunogen	Full length human recombinant protein of human PKLR (NP_000289) produced in HEK293T cell.
Gene Name	Homo sapiens pyruvate kinase L/R (PKLR), transcript variant 1, mRNA.
Symbol	PKLR
Function	Druggable Genome
Summary	The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Manufacturer - Format	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Buffer	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Dilution	WB 1:2000, IF 1:100, FLOW 1:100
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Glycolysis / Gluconeogenesis, Insulin signaling pathway, Maturity onset diabetes of the young, Metabolic pathways, Purine metabolism, Pyruvate metabolism, Type II diabetes mellitus

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ug

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Lieferung vsl. bis 15.01.2026

Express-Lieferung: 20 Tage sparen

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