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RUNX1T1 Mouse Monoclonal Antibody [Clone ID: LBI1H1]

RUNX1T1 Mouse Monoclonal Antibody [Clone ID: LBI1H1]

ArtNr	LBI-AMM12627V
Hersteller	Leading Biology
Menge	100 ul
Kategorie	Oncology Antibodies By Cell Type Hematology Leukemia
Typ	Antibody Monoclonal
Format	Liquid
Clon	LBI1H1
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Konjugat/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	AML1-MTG8, AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2
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Manufacturer - Category	mAbs-V
Manufacturer - Targets	RUNX1T1
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Acute myeloid leukemia, Pathways in cancer
Overview	RUNX1T1 (ETO) mouse monoclonal antibody, clone LBI1H1
Immunogen	Full length human recombinant protein of human RUNX1T1(NP_783553) produced in HEK293T cell.
Gene Name	RUNX1 partner transcriptional co-repressor 1
Symbol	RUNX1T1
Function	Transcription Factors
Summary	This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8; 21)(q22; q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
Manufacturer - Format	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Storage Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution	WB 1:2000, IF 1:100
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Acute myeloid leukemia, Pathways in cancer

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ul

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Lieferung vsl. bis 15.01.2026

Express-Lieferung: 16 Tage sparen

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