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Cbl c (CBLC) Mouse Monoclonal Antibody [Clone ID: LBI4E3]

Cbl c (CBLC) Mouse Monoclonal Antibody [Clone ID: LBI4E3]

ArtNr	LBI-AMM12919V
Hersteller	Leading Biology
Menge	100 ul
Kategorie	Oncology Antibodies By Cell Type Sarcoma
Typ	Antibody Monoclonal
Format	Liquid
Clon	LBI4E3
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Konjugat/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CBL-3, CBL-SL, RNF57
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Manufacturer - Category	mAbs-V
Manufacturer - Targets	CBLC
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Insulin signaling pathway, Jak-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Ubiquitin mediated proteolysis
Overview	CBLC mouse monoclonal antibody, clone LBI4E3
Immunogen	Human recombinant protein fragment corresponding to amino acids 244-474 of human CBLC(NP_036248) produced in HEK293T cell.
Gene Name	Cbl proto-oncogene C
Symbol	CBLC
Function	Druggable Genome
Summary	This gene encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]
Manufacturer - Format	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Storage Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution	WB 1:500, FLOW 1:100
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Insulin signaling pathway, Jak-STAT signaling pathway, Pathways in cancer, T cell receptor signaling pathway, Ubiquitin mediated proteolysis

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ul

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Lieferung vsl. bis 15.01.2026

Express-Lieferung: 16 Tage sparen

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