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IL1 alpha (IL1A) Mouse Monoclonal Antibody [Clone ID: LBI2D3]

ArtNr LBI-AMM13999V
Hersteller Leading Biology
Menge 100 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid
Clon LBI2D3
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias IL-1A, IL1, IL1-ALPHA, IL1F1
Lieferbar
Manufacturer - Category
mAbs-V
Manufacturer - Targets
IL1A
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research
Apoptosis, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Hematopoietic cell lineage, MAPK signaling pathway, Prion diseases, Type I diabetes mellitus
Overview
IL1A mouse monoclonal antibody, clone LBI2D3
Immunogen
Full length human recombinant protein of human IL1A(NP_000566) produced in HEK293T cell.
Gene Name
interleukin 1 alpha
Symbol
IL1A
Function
Druggable Genome, Secreted Protein
Summary
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq, Jul 2008]
Manufacturer - Format
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration
1 mg/ml
Storage Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution
WB 1:2000, IF 1:100
Purification
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway
Apoptosis, Cytokine-cytokine receptor interaction, Graft-versus-host disease, Hematopoietic cell lineage, MAPK signaling pathway, Prion diseases, Type I diabetes mellitus

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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