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BCL10 Mouse Monoclonal Antibody [Clone ID: LBI8G9]

BCL10 Mouse Monoclonal Antibody [Clone ID: LBI8G9]

ArtNr	LBI-AMM14667V
Hersteller	Leading Biology
Menge	100 ul
Kategorie	Oncology Antibodies By Organ Lymphatic System Cancer
Typ	Antibody Monoclonal
Format	Liquid
Clon	LBI8G9
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Konjugat/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	c-E10, CARMEN, CIPER, CLAP, IMD37, mE10
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Manufacturer - Category	mAbs-V
Manufacturer - Targets	BCL10
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	B cell receptor signaling pathway, T cell receptor signaling pathway
Overview	BCL10 mouse monoclonal antibody, clone LBI8G9
Immunogen	Full length human recombinant protein of human BCL10 (NP_003912) produced in HEK293T cell.
Gene Name	B-cell CLL/lymphoma 10
Symbol	BCL10
Function	Druggable Genome
Summary	This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. [provided by RefSeq, Jul 2008]
Manufacturer - Format	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Storage Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution	WB 1:500~2000
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	B cell receptor signaling pathway, T cell receptor signaling pathway

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Menge: 100 ul

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Lieferung vsl. bis 15.01.2026

Express-Lieferung: 17 Tage sparen

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