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AMACR Mouse Monoclonal Antibody [Clone ID: LBI2A11]

AMACR Mouse Monoclonal Antibody [Clone ID: LBI2A11]

ArtNr	LBI-AMM14831V
Hersteller	Leading Biology
Menge	100 ul
Kategorie	Metabolism Cholesterol & Lipid Metabolism Antibodies Enzymes Fatty Acid Catabolism
Typ	Antibody Monoclonal
Format	Liquid
Clon	LBI2A11
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Konjugat/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	AMACRD, CBAS4, RACE, RM
Lieferbar
Manufacturer - Category	mAbs-V
Manufacturer - Targets	AMACR
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Metabolic pathways, Primary bile acid biosynthesis
Overview	AMACR mouse monoclonal antibody, clone LBI2A11
Immunogen	Full length human recombinant protein of human AMACR (NP_055139) produced in HEK293T cell.
Gene Name	alpha-methylacyl-CoA racemase
Symbol	AMACR
Function	Druggable Genome
Summary	This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]
Manufacturer - Format	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Storage Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution	WB 1:2000, IHC 1:150
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Metabolic pathways, Primary bile acid biosynthesis

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Menge: 100 ul

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Lieferung vsl. bis 15.01.2026

Express-Lieferung: 21 Tage sparen

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