PCNA Mouse Monoclonal Antibody [Clone ID: LBI1H10]

PCNA

Base excision repair, Cell cycle, DNA replication, Mismatch repair, Nucleotide excision repair

Full length human recombinant protein of human PCNA (NP_002583) produced in E.coli.

PCNA

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)