GST3 (GSTP1) Mouse Monoclonal Antibody [Clone ID: LBI10H1]

GSTP1

Drug metabolism - cytochrome P450, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, Prostate cancer

Full length human recombinant protein of human GSTP1 (NP_000843) produced in E.coli.

GSTP1

Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases. [provided by RefSeq, Jul 2008]

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)