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DDIT3 Mouse Monoclonal Antibody [Clone ID: LBI1E7]

ArtNr LBI-AMM15404V
Hersteller Leading Biology
Menge 100 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid
Clon LBI1E7
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG1
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias CEBPZ, CHOP, CHOP-10, CHOP10, GADD153
Lieferbar
Manufacturer - Category
mAbs-V
Manufacturer - Targets
DDIT3
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research
MAPK signaling pathway
Overview
DDIT3 mouse monoclonal antibody, clone LBI1E7
Immunogen
Full length human recombinant protein of human DDIT3 (NP_004074) produced in E.coli.
Gene Name
DNA damage inducible transcript 3
Symbol
DDIT3
Function
Druggable Genome, Transcription Factors
Summary
This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010]
Manufacturer - Format
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration
1 mg/ml
Storage Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution
WB 1:2000
Purification
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway
MAPK signaling pathway

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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