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Acid sphingomyelinase (SMPD1) Mouse Monoclonal Antibody [Clone ID: LBI3H7]

ArtNr LBI-AMM16103VCF
Hersteller Leading Biology
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Format Lyophilized
Clon LBI3H7
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias ASM, ASMASE, NPD
Lieferbar
Manufacturer - Category
mAbs-V
Manufacturer - Targets
SMPD1
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research
Lysosome, Metabolic pathways, Sphingolipid metabolism
Overview
Carrier-free (BSA/glycerol-free) SMPD1 mouse monoclonal antibody, clone LBI3H7
Immunogen
Human recombinant protein fragment corresponding to amino acids 62-341 of human SMPD1 (NP_000534) produced in E.coli.
Gene Name
Homo sapiens sphingomyelin phosphodiesterase 1 (SMPD1), transcript variant 1, mRNA.
Symbol
SMPD1
Function
Druggable Genome, Transmembrane
Summary
The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2010]
Manufacturer - Format
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Dilution
WB 1:2000, IHC 1:150
Purification
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway
Lysosome, Metabolic pathways, Sphingolipid metabolism

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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