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PTCH1 Mouse Monoclonal Antibody [Clone ID: LBI1H10]

PTCH1 Mouse Monoclonal Antibody [Clone ID: LBI1H10]

ArtNr	LBI-AMM16138V
Hersteller	Leading Biology
Menge	100 ul
Kategorie	Oncology Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Melanoma Sarcoma
Typ	Antibody Monoclonal
Format	Liquid
Clon	LBI1H10
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Konjugat/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	BCNS, HPE7, NBCCS, PTC, PTC1, PTCH, PTCH11
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Manufacturer - Category	mAbs-V
Manufacturer - Targets	PTCH1
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer
Overview	PTCH1 mouse monoclonal antibody, clone LBI1H10
Immunogen	Human recombinant protein fragment corresponding to amino acids 770-1027 of human PTCH1 (NP_000255) produced in E.coli.
Gene Name	patched 1
Symbol	PTCH1
Function	Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Summary	This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently. [provided by RefSeq, Jul 2008]
Manufacturer - Format	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Storage Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution	WB 1:2000
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ul

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Lieferung vsl. bis 15.01.2026

Express-Lieferung: 17 Tage sparen

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