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GLI1 Mouse Monoclonal Antibody [Clone ID: LBI1F1]

ArtNr LBI-AMM16170V
Hersteller Leading Biology
Menge 100 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid
Clon LBI1F1
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG1
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias GLI
Lieferbar
Manufacturer - Category
mAbs-V
Manufacturer - Targets
GLI1
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research
Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer
Overview
GLI1 mouse monoclonal antibody, clone LBI1F1
Immunogen
Human recombinant protein fragment corresponding to amino acids 755-1106 of human GLI1 (NP_005260) produced in E.coli.
Gene Name
GLI family zinc finger 1
Symbol
GLI1
Function
Adult stem cells, Cancer stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Transcription Factors
Summary
This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Manufacturer - Format
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration
1 mg/ml
Storage Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution
WB 1:2000
Purification
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway
Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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