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EPOR Mouse Monoclonal Antibody [Clone ID: LBI4F12]

EPOR Mouse Monoclonal Antibody [Clone ID: LBI4F12]

ArtNr	LBI-AMM16564V
Hersteller	Leading Biology
Menge	100 ul
Kategorie	Oncology Antibodies By Cell Type Hematology Leukemia Lymphoma
Typ	Antibody Monoclonal
Format	Liquid
Clon	LBI4F12
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2a
Konjugat/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	EPO-R
Lieferbar
Manufacturer - Category	mAbs-V
Manufacturer - Targets	EPOR
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway
Overview	EPOR mouse monoclonal antibody, clone LBI4F12
Immunogen	Human recombinant protein fragment corresponding to amino acids 25-250 of human EPOR (NP_000112) produced in E.coli.
Gene Name	erythropoietin receptor
Symbol	EPOR
Function	Druggable Genome, Secreted Protein, Transmembrane
Summary	This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Manufacturer - Format	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Storage Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution	WB 1:2000, IHC 1:150
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway

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Menge: 100 ul

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Lieferung vsl. bis 15.01.2026

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