Laminin 5 (LAMB3) Mouse Monoclonal Antibody [Clone ID: LBI1H10]

LAMB3

ECM-receptor interaction, Focal adhesion, Pathways in cancer, Small cell lung cancer

Human recombinant protein fragment corresponding to amino acids 22-315 of human LAMB3(NP_000219) produced in E.coli.

LAMB3

The product encoded by this gene is a laminin that belongs to a family of basement membrane proteins. This protein is a beta subunit laminin, which together with an alpha and a gamma subunit, forms laminin-5. Mutations in this gene cause epidermolysis bullosa junctional Herlitz type, and generalized atrophic benign epidermolysis bullosa, diseases that are characterized by blistering of the skin. Multiple alternatively spliced transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)