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Retinoic Acid Receptor alpha (RARA) Mouse Monoclonal Antibody [Clone ID: LBI2C3]

ArtNr LBI-AMM17357VCF
Hersteller Leading Biology
Menge 100 ug
Kategorie
Typ Antibody Monoclonal
Format Lyophilized
Clon LBI2C3
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG1
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias NR1B1, RAR
Lieferbar
Manufacturer - Category
mAbs-V
Manufacturer - Targets
RARA
Storage Conditions
Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research
Acute myeloid leukemia, Pathways in cancer
Overview
Carrier-free (BSA/glycerol-free) RARA mouse monoclonal antibody, clone LBI2C3
Immunogen
Human recombinant protein fragment corresponding to amino acids 52-299 of human RARA(NP_000955) produced in E.coli.
Gene Name
Homo sapiens retinoic acid receptor alpha (RARA), transcript variant 1, mRNA.
Symbol
RARA
Function
Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
Summary
This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus. [provided by RefSeq, Sep 2010]
Manufacturer - Format
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Buffer
Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Dilution
WB 1:2000, IHC 1:150
Purification
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway
Acute myeloid leukemia, Pathways in cancer

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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