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PDX1 Mouse Monoclonal Antibody [Clone ID: LBI4D8]

PDX1 Mouse Monoclonal Antibody [Clone ID: LBI4D8]

ArtNr	LBI-AMM17733V
Hersteller	Leading Biology
Menge	100 ul
Kategorie	Metabolism Diabetes Glucose Homeostasis Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Clon	LBI4D8
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Konjugat/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	GSF, IDX-1, IPF1, IUF1, MODY4, PAGEN1, PDX-1, STF-1
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Manufacturer - Category	mAbs-V
Manufacturer - Targets	PDX1
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Maturity onset diabetes of the young, Type II diabetes mellitus
Overview	PDX1 mouse monoclonal antibody, clone LBI4D8
Immunogen	Full length human recombinant protein of human PDX1 (NP_000200) produced in E.coli.
Gene Name	pancreatic and duodenal homeobox 1
Symbol	PDX1
Function	Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors
Summary	The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq, Jul 2008]
Manufacturer - Format	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Storage Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution	WB 1:2000
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Maturity onset diabetes of the young, Type II diabetes mellitus

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ul

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Lieferung vsl. bis 15.01.2026

Express-Lieferung: 20 Tage sparen

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