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IGF1 Receptor (IGF1R) Mouse Monoclonal Antibody [Clone ID: LBI11E4]

IGF1 Receptor (IGF1R) Mouse Monoclonal Antibody [Clone ID: LBI11E4]

ArtNr	LBI-AMM18024VCF
Hersteller	Leading Biology
Menge	100 ug
Kategorie	Oncology Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Antibodies By Cell Type Blastoma Carcinoma Endocrine Regulation of Lipid Metabolism
Typ	Antibody Monoclonal
Format	Lyophilized
Clon	LBI11E4
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Konjugat/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	CD221, IGFIR, IGFR, JTK13
Lieferbar
Manufacturer - Category	mAbs-V
Manufacturer - Targets	IGF1R
Storage Conditions	Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Adherens junction, Colorectal cancer, Endocytosis, Focal adhesion, Glioma, Long-term depression, Melanoma, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer
Overview	Carrier-free (BSA/glycerol-free) IGF1R mouse monoclonal antibody, clone LBI11E4
Immunogen	Human recombinant protein fragment corresponding to amino acids 741-935 of human IGF1R(NP_000866) produced in Insect.
Gene Name	Homo sapiens insulin like growth factor 1 receptor (IGF1R), transcript variant 1, mRNA.
Symbol	IGF1R
Function	Druggable Genome, Protein Kinase, Transmembrane
Summary	This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May
Manufacturer - Format	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Storage Buffer	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Dilution	WB 1:500
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Adherens junction, Colorectal cancer, Endocytosis, Focal adhesion, Glioma, Long-term depression, Melanoma, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ug

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Lieferung vsl. bis 15.01.2026

Express-Lieferung: 20 Tage sparen

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