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IL24 Mouse Monoclonal Antibody [Clone ID: LBI4E1]

IL24 Mouse Monoclonal Antibody [Clone ID: LBI4E1]

ArtNr	LBI-AMM18976V
Hersteller	Leading Biology
Menge	100 ul
Kategorie	Antibodies Cell Biology Cell Culture Cytokines
Typ	Antibody Monoclonal
Format	Liquid
Clon	LBI4E1
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Konjugat/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	C49A, FISP, IL10B, MDA7, MOB5, ST16
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Manufacturer - Category	mAbs-V
Manufacturer - Targets	IL24
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
Overview	IL24 mouse monoclonal antibody, clone LBI4E1
Immunogen	Human recombinant protein fragment corresponding to amino acids 52-206 of human IL24(NP_006841) produced in E.coli.
Gene Name	interleukin 24
Symbol	IL24
Function	Druggable Genome, Secreted Protein
Summary	This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Manufacturer - Format	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Storage Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution	WB 1:500, IHC 1:150
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway

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Menge: 100 ul

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Lieferung vsl. bis 15.01.2026

Express-Lieferung: 17 Tage sparen

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