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MLH1 Mouse Monoclonal Antibody [Clone ID: LBI2A8]

MLH1 Mouse Monoclonal Antibody [Clone ID: LBI2A8]

ArtNr	LBI-AMM20494V
Hersteller	Leading Biology
Menge	100 ul
Kategorie	Oncology Antibodies By Cell Type Carcinoma Glioma Hematology Lymphoma Myeloma Melanoma Sarcoma Mesothelioma
Typ	Antibody Monoclonal
Format	Liquid
Clon	LBI2A8
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG2a
Konjugat/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	COCA2, FCC2, hMLH1, HNPCC, HNPCC2, MMRCS1
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Manufacturer - Category	mAbs-V
Manufacturer - Targets	MLH1
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Colorectal cancer, Endometrial cancer, Mismatch repair, Pathways in cancer
Overview	MLH1 mouse monoclonal antibody, clone LBI2A8
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-298 of human MLH1 (NP_000240) produced in E.coli.
Gene Name	mutL homolog 1
Symbol	MLH1
Function	Druggable Genome
Summary	This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined. [provided by RefSeq, Nov 2009]
Manufacturer - Format	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Storage Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution	WB 1:500
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Colorectal cancer, Endometrial cancer, Mismatch repair, Pathways in cancer

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ul

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Lieferung vsl. bis 15.01.2026

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