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HB EGF (HBEGF) Mouse Monoclonal Antibody [Clone ID: LBI10B1]

HB EGF (HBEGF) Mouse Monoclonal Antibody [Clone ID: LBI10B1]

ArtNr	LBI-AMM20743V
Hersteller	Leading Biology
Menge	100 ul
Kategorie	Oncology Neuroscience Neural Signaling Antibodies By Cell Type Carcinoma
Typ	Antibody Monoclonal
Format	Liquid
Clon	LBI10B1
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b
Konjugat/Tag	Unconjugated
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	DTR, DTS, DTSF, HEGFL
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Manufacturer - Category	mAbs-V
Manufacturer - Targets	HBEGF
Storage Conditions	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research	Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, GnRH signaling pathway
Overview	HBEGF mouse monoclonal antibody, clone LBI10B1
Immunogen	Human recombinant protein fragment corresponding to amino acids 20-208 of human HBEGF (NP_001936) produced in E.coli.
Gene Name	heparin binding EGF like growth factor
Symbol	HBEGF
Function	Druggable Genome, Secreted Protein, Transmembrane
Summary	Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor. [UniProtKB/Swiss-Prot Function]
Manufacturer - Format	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Storage Buffer	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution	WB 1:2000
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway	Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, GnRH signaling pathway

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ul

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Lieferung vsl. bis 15.01.2026

Express-Lieferung: 17 Tage sparen

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