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JAK3 Mouse Monoclonal Antibody [Clone ID: LBI2B4]

ArtNr LBI-AMM20929V
Hersteller Leading Biology
Menge 100 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid
Clon LBI2B4
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1
Konjugat/Tag Unconjugated
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK
Lieferbar
Manufacturer - Category
mAbs-V
Manufacturer - Targets
JAK3
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Field of Research
Chemokine signaling pathway, Jak-STAT signaling pathway, Primary immunodeficiency
Overview
JAK3 mouse monoclonal antibody, clone LBI2B4
Immunogen
Human recombinant protein fragment corresponding to amino acids 811-1124 of human JAK3 (NP_000206) produced in E.coli.
Gene Name
Janus kinase 3
Symbol
JAK3
Function
Druggable Genome, Protein Kinase
Summary
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008]
Manufacturer - Format
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration
1 mg/ml
Storage Buffer
PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Dilution
WB 1:500
Purification
Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Pathway
Chemokine signaling pathway, Jak-STAT signaling pathway, Primary immunodeficiency

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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