Anti-Mouse KDEL Receptor [Clone KR-10] - 100 µg

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Next Day 2 - 8°C

KDEL receptor, an integral membrane protein, facilitates the retrieval of soluble endoplasmicreticulum (ER) luminal proteins bearing the four amino acid retention motif KDEL from the Golgiapparatus. The sequence of KDEL receptor is very similar to that of the yeast protein Erd2p, areceptor for proteins containing the tetrapeptide HDEL, the yeast ER retention signal. KDELreceptors interact with GAP (GTPase-activating protein) of ARF1, a small GTP-binding proteininvolved in COPI-dependent vesicle transport. KEDL receptors may recruit cytosolic ARF1 tomembranes and regulate vesicle budding.

1.0 mg/ml