Anti-Sodium Iodide Symporter Antibody (11563) - 100 µg

Antibody Products>Ion Channel Antibodies|Primary Monoclonal Antibodies|Products

Next Day 2 - 8°C

The sodium iodide symporter (NIS) is an ion pump that actively transports iodide across the basolateral membrane into thyroid epithelial cells. This is an important step in the process of iodide organification and the formation of triiodothyronine and thyroxine. The importance of NIS is related to its role in thyroid function, the pathogenesis of thyroid disease, and its expression (or lack of expression) in thyroid malignancies. It has also been suggested that NIS may represent an autoantigen in autoimmune disease of the thyroid.

1.0 mg/ml