Anti-Heme Oxygenase-1 Antibody (Clone 6B8-2F2) - 100 µg

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Next Day 2 - 8°C

Heme oxygenase (HO) is a membrane-bound enzyme that catalyzes the degradation of heme into biliverdin, carbon monoxide (CO), and free iron. Biliverdin is subsequently converted to bilirubin, a potent antioxidant. There are two main isoforms of HO: the inducible HO-1 and the constitutively expressed HO-2.HO-1 is upregulated in response to a broad range of stress signals, including oxidative stress, inflammatory cytokines, heat shock, and transforming growth factor-beta (TGF-β). Its induction is considered a key cellular protective mechanism, helping to mitigate oxidative damage through the production of antioxidant byproducts. Due to its role in cytoprotection and inflammation modulation, HO-1 is widely studied in the context of cardiovascular, neurodegenerative, and inflammatory diseases.

1.0 mg/ml