Anti-Superoxide Dismutase 1 (SOD1) EDI [Polyclonal] - 100 µg

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Superoxide dismutase (SOD) is an endogenously produced intracellular enzyme that catalyzesthe dismutation of the superoxide radical O2- to oxygen and hydrogen peroxide which are thenmetabolized to H2O and O2 by catalase and glutathione peroxidase. SODs play an important rolein antioxidant defense mechanisms. Three different SOD isoenzymes are found in mammaliancells: SOD1, SOD2, and SOD3. SOD1 contains Cu and Zn ions and exists as a homodimer incell cytoplasm. The two subunits of ~16kDa each are linked by two cysteines that form an intrasubunit disulfide bridge. Misfolding of SOD1 has been implicated in Amyotrophic LateralSclerosis (ALS).

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