Anti-Valproic Acid [5 Clones] — Library Pack - 5x 100μg

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Next Day 2 - 8°C

Valproic acid is primarily used to treat epilepsy and bipolar disorder and to prevent migraine headaches. It has recently been shown to protect against a seizure-induced reduction in phosphatidylinositol (3, 4, 5)-trisphosphate (PIP3) as a potential therapeutic mechanism. In addition, its anticonvulsant effect has been attributed to the blockade of voltage-dependent sodium channels and increased brain levels of gamma-aminobutyric acid (GABA). Valproic acid was first made in 1881 and came into medical use in 1962. It is on the World Health Organization's List of Essential Medicines.

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