Anti-Copper-Transporting ATPase1 Antibody (56516) - 100 µg

Antibody Products>Neuroscience and Signal Transduction Antibodies|Products

Next Day 2 - 8°C

The copper efflux transporters ATP7A and ATP7B sequester intracellular copper into the vesicular secretory pathway for export from cells. ATP7A (also known as Copper-Transporting ATPase1) functions as a transmembrane copper-translocating P-type ATPase and plays a vital role in systemic copper absorption in the gut and copper reabsorption in the kidney. Although ATP7A is not detectable in most normal tissues, it is expressed in many common tumor types. Increased expression of ATP7A renders tumor cells resistant to cisplatin and carboplatin.

1.0 mg/ml