Anti-Synaptotagmin-7 Antibody (56533) - 100 µg

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Next Day 2 - 8°C

Synaptotagmins constitute a family of membrane trafficking proteins that are characterized by an N terminal trans- membrane region (TMR), a variable linker, and two C-terminal C2 domains: C2A and C2B. There are 15 members in the mammalian synaptotagmin family. The synaptotagmins are integral membrane proteins of synaptic vesicles thought to act as Ca+2 sensors in vesicular trafficking and exocytosis. Calcium binding to synaptotagmin triggers neurotransmitter release at the synapse. The first C2 domain mediates Ca+2-dependent phospholipid binding. The second C2 domain mediates interaction with Stonin 2.

1.0 mg/ml