Mikrogen Diagnostik <i>recom</i>Line HantaPlus IgM Lateral Strip Test Kit - 20 Tests

Next Day 2 - 8°C

Strip-Immunoassay with antigens produced by recombinant techniques for the detection of IgG and IgM antibodies againstHantavirus (serotypes Puumala (PuN), Sin Nombre (SinN), Hantaan (HaN), Dobrava (DobN) and Seoul (SeoN)) as well as SandflyFever Virus (SFFV) serotypes Toscana and Sicilian.Most of the Bunyaviruses can be found in the tropics and subtropics. An exceptionare the genera of Hantavirus und Phlebovirus which are also represented in Europeas well.Hantavirus: Different rodent species are vectors for the different hantavirus serotypes Puumala, Sin Nombre, Dobrava, Hantaan and Seoul. Many other serotypes aredescribed in literature to be found in isolated areas. Based on a significant homology within the N-terminal part of the virus nucleocapsid antigen, hantaviruses canbe devided in two serological groups, Puumala and Sin Nombre, and the group ofHantaan, Dobrava and Seoul. Hantaviruses are transmitted via stirred and inhaleddust, contaminated with rodents droppings. Hantavirus outbreaks regularly monitored every two to three years are very likely interconnected with an excessivefood supply for the vector animals (rodents) and their proliferation. Typical peaks incase numbers can be related to holiday seasons and spring-cleaning activities, likecleaning basement, outbuilding or summer houses with unattended rodent infestation. There are no cases described for human to human transmission. The onset of ahantavirus infection is characterized by flu-like symptoms. The Puumalavirus prevelant in Europe can cause renal failures requiring hemodialysis and intensive caretreatment. This Nephropathia epidemica (NE), describes a moderate form of thehemorrhagic fever with renal syndrom (HFRS), caused by infections with the virustypes Dobrava, Hantaan and Seoul. The lethality of a Puumala infection is reportedto be less than 1%. An infection with Sin Nombre or Andes virus may result in asevere Hantavirus Pulmonary Syndrom (HPS) with lethality rates reported over 30%.Sandfly Fever Virus (SFFV): A few Bunyaviruses in Europe are transmitted by theSandfly (Phlebotomus pappatasi), which is present in the Mediterranean area.Sandfly Fever, synonym Pappatasi Fever, is characterized by fever symptoms andheadache. More severe courses with fever, strong, frontal headache and an asepticmeningitis with neurological symptoms are described for infections with the serotypes Toscana and Sicilian.Research Use Only. For Sale In the United States Only. To purchase outside of the US, please contact Mikrogen.