Anti-Annexin A1 [A1A7] - 100 µg

Antibody Products>Apoptosis Antibodies|Primary Monoclonal Antibodies|Products

Next Day 2 - 8°C

Annexin 1 belongs to a family of Ca(2+)- dependent phospholipid binding proteins which have molecular weights of approximately 35-40kDa and are localized on the cytosolic face of the plasma membrane. Annexin 1, an endogenous anti-inflammatory protein, has roles in many diverse cellular functions, such as membrane aggregation, inflammation, phagocytosis, proliferation, and apoptosis. Annexin 1 also possesses phosphorylation sites for important proliferative signaling molecules e.g., EGF receptor tyrosine kinase and PKC. This suggests that Annexin 1 may have a role in certain signaling pathways important in cancer. However, the exact mechanisms through which Annexin 1 exerts some or all of its effects are still not clearly understood, and may reveal important functions of Annexin 1 in tumorigenesis and cancer development.

Lyophilized, 0.1M Tris, 0.1M glycine, 2% sucrose.