Anti-Calnexin [C2A1] - 100 µg

Antibody Products>Neuroscience and Signal Transduction Antibodies|Primary Monoclonal Antibodies|Products

Next Day 2 - 8°C

Calnexin is a ~90 kDa integral protein of the endoplasmic reticulum; it is also referred to as IP90, p88 and p90. It consists of a 50kDa N-terminal calcium- binding luminal domain, a single transmembrane helix, and a short acidic cytoplasmic tail. Its positively charged cytosolic residues ensure its retention in the endoplasmic reticulum. Calnexin together with calreticulin play a key role in glycoprotein folding by interacting with folding intermediates via their monoglycosylated glycans. Calnexin has also been shown to associate with the major histocompatability complex class I heavy chains, partial complexes of the T cell receptor, and B cell surface immunoglobulin.

Lyophilized, 0.1M Tris, 0.1M glycine, 2% sucrose, 1mg/ml.