MNS

Hersteller MedChem Express
Kategorie
Typ Inhibitors
Specific against other
Menge 10mM*1mL (in DMSO)
ArtNr HY-78263-10mM
Eclass 6.1 30220300
Eclass 9.0 32160605
Lieferbar
Synonyms
NSC 170724, 5-(2-Nitrovinyl)benzodioxole
CAS No.
1485-00-3
Purity
>98%
MW
1931562
Formula
C9H7NO4
Solubility
10 mM in DMSO
Biological Description
MNS is a potent and selective inhibitor of Src and Syk tyrosine kinases.
target: src, syk. [1]
IC50:29.3 (src), 2.5 uM (syk); [1]
In vitro: no direct effects on protein kinase C, Ca2+ mobilization, Ca2+-dependent enzymes, PKC activation. MNS potently prevents GPIIb/IIIa activation and platelet aggregation without directly affecting other signaling pathways required for platelet activation. [1] [2] MNS is much more potent than genistein in inhibiting platelet aggregation and protein tyrosine phosphorylation. [2]
Free  Sample
Available in quantities of 0, 5mg-1mg. Three different samples per customer per year!
Menge: 10mM*1mL (in DMSO)
Lieferbar: In stock
Listenpreis: 114,29 €
Rabatt: -10,0%
Preis: 102,86 €
Sie sparen: 11,43 €
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