Guanidine (hydrochloride)

Hersteller MedChem Express
Kategorie
Typ Inhibitors
Specific against other
Clon N/A
Menge 10g
ArtNr HY-B0178A-10g
Eclass 6.1 30220300
Eclass 9.0 32160605
Lieferbar
Synonyms
Guanidinium chloride, Aminoformamidine Hydrochloride
CAS No.
50-01-1
Purity
>98%
MW
9553144
Formula
CH6ClN3
Solubility
10 mM in DMSO
Biological Description
Guanidine HCl, the crystalline compound of strong alkalinity formed by the oxidation of guanine, is a normal product of protein metabolism and a protein denaturant.
Target: Others
Guanidine HCl is the most popular protein denaturant. Analysis of unfolding transitions by Guanidine HCl provides several important parameters regarding the mechanism of conformational stability of proteins. Guanidine HCl at low concentrations refolds acid-unfolds apomyoglobin and cytochrome c, stabilizing the molten globule state. Guanidine HCl (> 1 M) causes co-operative unfolding of the molten globule state [1]. Guanidine HCl at millimolar concentrations, is able to causes efficient loss of the normally stable [PSI+] element from yeast cells. 5 mM Guanidine HCl in growth media cures [PSI+] and other prions of yeast. 5 mM Guanidine HCl significantly reduces Hsp104-mediated basal and acquired thermotolerance by 30-fold and 50 fold, respectively. Guanidine HCl also reduces the ability of Hsp104 to restore activity of thermally denatured luciferase [2].
Free  Sample
Available in quantities of 0, 5mg-1mg. Three different samples per customer per year!

Sicherheitsdatenblatt

HY-B0178A-10g.pdf

Menge: 10g
Lieferbar: In stock
Listenpreis: 108,93 €
Rabatt: -10,0%
Preis: 98,04 €
Sie sparen: 10,89 €
lieferbar

Angebot anfordern

Fragen zum Produkt?

Ihr Ansprechpartner:

Arne Pelz

sales@hoelzel.de

 
Schließen