Rifapentine

Hersteller MedChem Express
Kategorie
Typ Inhibitors
Specific against other
Clon N/A
Menge 50mg
ArtNr HY-B0269-50mg
Eclass 6.1 30220300
Eclass 9.0 32160605
Lieferbar
Synonyms
DL 473, Cyclopentylrifampicin
CAS No.
61379-65-5
Purity
>98%
MW
8770306
Formula
C47H64N4O12
Solubility
10 mM in DMSO
Biological Description
Rifapentine (Priftin; DL 473) is an antibiotic compound used in the treatment of tuberculosis.
Target: Antibacterial
Rifapentine inhibits DNA-dependent RNA polymerase activity in susceptible cells. Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian enzyme. A review of alternative regimens for prevention of active tuberculosis in HIV-negative individuals with latent TB found that a weekly, directly observed regimen of rifapentine with isoniazid for three months was as effective as a daily, self -administered regimen of isoniazid for nine months. But the rifapentine-isoniazid regimen had higher rates of treatment completion and lower rates of hepatotoxicity . However the rates of treatment-limiting adverse events were higher in the rifapentine-isoniazid regimen [1].

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Sicherheitsdatenblatt

HY-B0269-50mg.pdf

Menge: 50mg
Lieferbar: In stock
Listenpreis: 118,57 €
Rabatt: -10,0%
Preis: 106,71 €
Sie sparen: 11,86 €
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