Synephrine (hydrochloride)

Hersteller MedChem Express
Kategorie Produkte / Inhibitors
Typ Inhibitors
Specific against other
Clon N/A
Menge 10mM*1mL (in DMSO)
ArtNr HY-N0132A-10mM
Eclass 6.1 30220300
Eclass 9.0 32160605
Lieferbar
Synonyms
Oxedrine hydrochloride
CAS No.
5985-28-4
Purity
>98%
MW
203666
Formula
C9H14ClNO2
Solubility
DMSO: >= 52 mg/mL
Biological Description
Synephrine Hcl(Oxedrine) is an alkaloid; synephrine produces most of its biological effects by acting as an agonist at adrenergic receptors.
IC50 value:
Target: adrenergic receptor agonist
There is some evidence that synephrine also has weak activity at 5-HT receptors, and that it interacts with TAAR1 (trace adrenergic amine receptors). d-synephrine inhibited the uptake of [3H]-norepinephrine with an IC50 = 5.8 uM; l-synephrine was less potent (IC50 = 13.5 uM). d-Synephrine also competitively inhibited the binding of nisoxetine[m] to rat brain cortical slices, with a Ki = 4.5 uM; l-synephrine was less potent (Ki = 8.2 uM). In experiments on the release of [3H]-norepinephrine from rat brain cortical slices, however, the l-isomer of synephrine was a more potent enhancer of the release (EC50 = 8.2 uM) than the d-isomer (EC50 = 12.3 uM). This enhanced release by l-synephrine was blocked by nisoxetine.
Free  Sample
Available in quantities of 0, 5mg-1mg. Three different samples per customer per year!
Menge: 10mM*1mL (in DMSO)
Lieferbar: In stock
Listenpreis: 111,71 €
Preis: 111,71 €
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