Omeprazole (H 16868)

Description: Omeprazole (H 16868; trade names: Prilosec, Zegerid), approved by the FDA, is available as a prescription and over-the-counter (OTC) drug used as a treatment for frequent heartburn. Omeprazole is a proton pump inhibitor with an IC50 of 5.8 uM, it is used to treat dyspepsia, peptic ulcer disease, gastroesophageal reflux disease (GERD), laryngopharyngeal reflux, and Zollinger–Ellison syndrome. Omeprazole. It is also used to prevent upper gastrointestinal bleeding in people who are at high risk. Omeprazole is a proton pump inhibitor and as such blocks the release of stomach acid.

References: J Biol Chem. 1997 May 9; 272(19):12705-13; Am J Physiol. 1994 Apr; 266(4 Pt 1):G745-58.

Related CAS#:95510-70-6 (sodium); 119141-88-7 (S-isomer); 95510-71-7 (potassium); 73590-85-9 (Omeprazole metabolite Omeprazole sulfide; Ufiprazole; Omeprazole sulfide); 88546-55-8 (Omeprazole metabolite Omeprazole sulfone; Omeprazole sulfone; Omeprazole sulphone); 922731-01-9 (Omeprazole D3; H 16868 D3); 73590-58-6 (free form)