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Trelagliptin succinate (SYR-472)

Trelagliptin succinate (SYR-472)

ArtNr	V2555-250mg
Hersteller	InvivoChem LLC
CAS-Nr.	1029877-94-8
Menge	250 mg
Quantity options	100 mg 1 g 25 mg 500 mg 50 mg
Kategorie	Reagents & Chemicals Molecules
Typ	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
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Description	InvivoChem Cat #:V2555CAS #:1029877-94-8Purity >=98% Description: Trelagliptin succinate (also known as SYR-472 succinate) is a potent, highly selective, long-actingDPP-4 (dipeptidyl peptidase-4) inhibitor under development by Takeda forthe treatment of type 2 diabetes (T2D)..Once-weekly Trelagliptin treatment produced clinically and statisticallysignificant improvements in glycaemic control in patients with type 2diabetes. It was well tolerated and might be a new treatment option forpatients with this disease. Trelagliptin was approved in Japan for thetreatment of type 2 diabetes mellitus (T2DM). (also known as SYR-472 succinate) is a potent, highly selective, long-actingDPP-4 (dipeptidyl peptidase-4) inhibitor under development by Takeda forthe treatment of type 2 diabetes (T2D)..Once-weekly Trelagliptin treatment produced clinically and statisticallysignificant improvements in glycaemic control in patients with type 2diabetes. It was well tolerated and might be a new treatment option forpatients with this disease. Trelagliptin was approved in Japan for thetreatment of type 2 diabetes mellitus (T2DM). References: Lancet Diabetes Endocrinol. 2014 Feb; 2(2):125-32. Related CAS #:1029877-94-8 (succinate) 865759-25-7 (free base) elated CAS #:1029877-94-8 (succinate) 865759-25-7 (free base)
Molecular Weight (MW)	475.47
Formula	C22H26FN5O6
CAS No.	1029877-94-8
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 10 mM
	Water: N/A
	Ethanol: N/A
Solubility (In vivo)	Chemical Name: (R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2, 4-dioxo-3, 4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile succinate InChi Key: OGCNTTUPLQTBJI-XFULWGLBSA-N InChi Code: InChI=1S/C18H20FN5O2.C4H6O4/c1-22-17(25)8-16(23-6-2-3-15(21)11-23)24(18(22)26)10-13-7-14(19)5-4-12(13)9-20; 5-3(6)1-2-4(7)8/h4-5, 7-8, 15H, 2-3, 6, 10-11, 21H2, 1H3; 1-2H2, (H, 5, 6)(H, 7, 8)/t15-; /m1./s1 SMILES Code: O=C(O)CCC(O)=O.N#CC1=CC=C(F)C=C1CN(C(N2C)=O)C(N3C[CH](N)CCC3)=CC2=O
Synonyms	SYR-472; SYR472; SYR 472; SYR 472; Trelagliptin, Trelagliptin succinate; brand name: Zafatek.

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Menge: 250 mg

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Lieferung vsl. bis 02.10.2025

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